Ongoing Research
Surveillance for Enteric Fever in Asia project(SEAP)
SEAP is a multi-site prospective study aiming to generate data to inform policy recommendations on enteric fever prevention and control, as well as facilitate typhoid vaccine implementation.
Analysis of serum YncE responses in patients with S. Typhi/Para Typhi carriage following elective cholecystectomy
We are at a critical and rapidly evolving juncture for global typhoid control. There is a spreading extensively drug resistant S. Typhi outbreak in Pakistan, and there have been increasing efforts toward typhoid control.
Multicenter, Observer-Blinded, Randomized, Active Controlled Trial to Cholera Vaccine-Simplified
This is a multicenter, randomized, observer-blinded, controlled study to evaluate immune non-inferiority and safety of OCV-S compared to Shanchol™ in 1 to 40 years old healthy Nepalese participants
Study on seroprevalence of Hepatitis E in Nepal
Hepatitis E is primarily a waterborne disease transmitted by fecal-to-oral route and a major public health concern in developing countries.
Breakthrough infection of COVID-19 in vaccinated healthcare workers at Dhulikhel Hospital and associated factors
With the massive outbreak of pneumonia reported in Wuhan, China in December 2019, the disease was named as Coronavirus disease 2019 (COVID-19). With the declaration of pandemic of COVID-19 on 11th March 2020, caused by severe acute respiratory syndrome-coronavirus-2
Deciphering the whole genomic sequence of SARS-CoV-2 using next-generation sequencing technology in COVID-19 patients of Nepal
The spread of SARS-CoV-2 has become a global public health crisis. In Nepal, since the first detection of COVID-19 in January 2020, the total cases have rose to almost a million with around 12,000 deaths.
In Nepal, there occurs an enigmatic ocular disease called Seasonal Hyperacute Pan uveitis (SHAPU) which presents as a rare endogenous pediatric endophthalmitis but
Using metagenomic next-generation sequencing technology to determine the etiologies of severe or fatal Acute Encephalitis Syndrome in Nepal
Acute Encephalitis Syndrome (AES) is characterized by acute onset of fever and altered sensorium followed by rapidly worsening clinical condition and even death.